Assessment of the effect of alpha-tocopherol on the course of newly diagnosed pulmonary sarcoidosis: a comparative study
| Autor: | A. A. Vizel, D. A. Culver, I. Yu. Vizel, G. R. Shakirova, E. A. Bakunina |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Computed tomography 030204 cardiovascular system & hematology Löfgren syndrome Gastroenterology 03 medical and health sciences chemistry.chemical_compound Diseases of the respiratory system 0302 clinical medicine Pulmonary sarcoidosis alpha-tocopherol Internal medicine medicine follow-up Mild form sarcoidosis Stage (cooking) medicine.diagnostic_test treatment RC705-779 business.industry Vitamin E General Medicine medicine.disease 030228 respiratory system chemistry comparison Sarcoidosis alpha-Tocopherol business |
| Zdroj: | Tuberkulez i Bolezni Lëgkih, Vol 98, Iss 10, Pp 33-40 (2020) |
| ISSN: | 2542-1506 2075-1230 |
| Popis: | The objective:to compare the results of follow-up over patients with a mild form of pulmonary sarcoidosis who received alpha-tocopherol and those receiving no treatment.Subjects and methods.The results of follow-up over 80 sarcoidosis patients were retrospectively analyzed – two groups of 40 patients enrolled according to the copy – pair principle (gender, age, initial X-ray stage, Löfgren syndrome, and follow-up duration). The only sign that statistically distinguished the groups was a high frequency of complaints about weakness in those who received vitamin E – 55% versus 30% (p < 0.05). The follow-up period for patients in both groups was a year or more (a control point). The database was maintained and processed using SPSS-18, Windows 10. A clear advantage of vitamin E administration was revealed when comparing the data of computed tomography, which resulted in improvement in 87.5%, and the disease progressed in 2.5%, while in the group receiving no treatment – 60 and 12.5%, respectively. The OR of improvement in computed tomography with alpha-tocopherol versus the group receiving no treatment made 4.67 (95% CI, 1.51-14.46).Conclusion.The use of vitamin E in mild forms of thoracic sarcoidosis gives a better result compared to the group receiving no treatment. |
| Databáze: | OpenAIRE |
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