Dose dependence of susceptibility and transmission for an Argentinean West Nile virus strain in local Culex pipiens quinquefasciatus (Diptera: Culicidae)
| Autor: | Adrián Diaz, Octavio Giayetto, Mauricio Beranek, Franco Nicolas Nazar |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Culex West Nile virus viruses 030231 tropical medicine Population Mosquito Vectors medicine.disease_cause Virus law.invention 03 medical and health sciences 0302 clinical medicine law medicine Animals Humans education education.field_of_study biology Strain (biology) Public Health Environmental and Occupational Health General Medicine biology.organism_classification Virology 030104 developmental biology Infectious Diseases Transmission (mechanics) Culicidae Vector (epidemiology) Parasitology Viral load West Nile Fever |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 115(9) |
| ISSN: | 1878-3503 |
| Popis: | Background West Nile virus (WNV) activity has been documented in the central region of Argentina since 2005, but its maintenance network has not been elucidated yet. Methods We evaluated the susceptibility to WNV oral infection and transmission in a Culex pipiens quinquefasciatus mosquito population by means of a dose-dependent vector competence assay. Mosquitoes were orally infected with five different viral loads and evaluated for viral infection, dissemination and transmission. Results The evaluated population was susceptible to WNV oral infection. Disseminated infections were detected in all the viral doses but transmission was only detected in the higher doses (6 and 7 log10 plaque-forming units/ml). A linear relationship between doses and transmission rates could be established. Conclusions A minimum transmission threshold suggests that the Cu. p. quinquefasciatus from Argentina could acquire WNV infection from local urban birds and transmit the virus. |
| Databáze: | OpenAIRE |
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