Evaluation of attenuation correction in cardiac PET using PET/MR
| Autor: | Houman Sotoudeh, Shivak Sharma, Jonathan McConathy, Robert J. Gropler, Xingyu Nie, Pamela K. Woodard, Eric Novak, Jeffrey M. C. Lau, Richard Laforest, Agus Priatna |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty For Attenuation Correction 030204 cardiovascular system & hematology Sensitivity and Specificity Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging medicine.diagnostic_test business.industry Phantoms Imaging Myocardial Perfusion Imaging Reproducibility of Results Magnetic resonance imaging Pet imaging Middle Aged Image Enhancement Magnetic Resonance Imaging Positron emission tomography Cardiac PET Clinical diagnosis Positron-Emission Tomography Feasibility Studies Female Radiology Cardiology and Cardiovascular Medicine business Nuclear medicine Artifacts Correction for attenuation |
| Zdroj: | Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 24(3) |
| ISSN: | 1532-6551 |
| Popis: | Simultaneous acquisition Positron emission tomography/magnetic resonance (PET/MR) is a new technology that has potential as a tool both in research and clinical diagnosis. However, cardiac PET acquisition has not yet been validated using MR imaging for attenuation correction (AC). The goal of this study is to evaluate the feasibility of PET imaging using a standard 2-point Dixon volume interpolated breathhold examination (VIBE) MR sequence for AC. Evaluation was performed in both phantom and patient data. A chest phantom containing heart, lungs, and a lesion insert was scanned by both PET/MR and PET/CT. In addition, 30 patients underwent whole-body 18F-fluorodeoxyglucose PET/CT followed by simultaneous cardiac PET/MR. Phantom study showed 3% reduction of activity values in the myocardium due to the non-inclusion of the phased array coil in the AC. In patient scans, average standardized uptake values (SUVs) obtained by PET/CT and PET/MR showed no significant difference (n = 30, 4.6 ± 3.5 vs 4.7 ± 2.8, P = 0.47). There was excellent per patient correlation between the values acquired by PET/CT and PET/MR (R 2 = 0.97). Myocardial SUVs PET imaging using MR for AC shows excellent correlation with myocardial SUVs obtained by standard PET/CT imaging. The 2-point Dixon VIBE MR technique can be used for AC in simultaneous PET/MR data acquisition. |
| Databáze: | OpenAIRE |
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