Association between ideal cardiovascular health and markers of subclinical cardiovascular disease
| Autor: | Daniel Shpilsky, Claudia Bambs, Sanjay R. Patel, Oladipupo Olafiranye, Steven E. Reis, Aryan Aiyer, Kevin E. Kip, Sebhat Erqou |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Health Status Cardiovascular health Clinical Investigations Disease 030204 cardiovascular system & hematology Carotid Intima-Media Thickness Risk Assessment 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Prevalence Humans Medicine cardiovascular diseases 030212 general & internal medicine Risk factor Reactive hyperemia Aged Retrospective Studies Ultrasonography Subclinical infection Ideal (set theory) Framingham Risk Score business.industry Carotid ultrasonography General Medicine Middle Aged Pennsylvania Coronary Vessels Carotid Arteries Cross-Sectional Studies Cardiovascular Diseases Cardiology Female Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Clinical Cardiology. 41:1593-1599 |
| ISSN: | 0160-9289 |
| DOI: | 10.1002/clc.23096 |
| Popis: | BACKGROUND: Ideal cardiovascular health (CVH) was proposed by the American Heart Association to promote population health. We aimed to characterize the association between ideal CVH and markers of subclinical cardiovascular disease (CVD). HYPOTHESIS: We hypothesized that ideal CVH is associated with several markers of subclinical CVD. METHODS: We used data from the Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) study. We assigned 1 for each of the ideal CVH factors met. Endothelial function, expressed as Framingham reactive hyperemia index (fRHI), was measured using the EndoPAT device. Coronary artery calcium (CAC) and carotid intima‐media thickness (CIMT) were quantified using electron beam computed tomography and carotid ultrasonography, respectively. RESULTS: A total of 1933 participants (mean [SD] age: 59 [7.5] years, 34% male, 44% black) were included. The mean number of ideal CVH factors met was 2.3 ± 1.3, with blacks having significantly lower score compared to whites (2.0 ± 1.2 vs 2.5 ± 1.4, respectively; P < 0.001). Seven hundred and eighty‐nine participants (41%) achieved ≥3 ideal CVH factors. Participants with ≥3 ideal CVH factors (compared to those with 100 Agatston units. CONCLUSION: In a community‐based study with low prevalence of ideal CVH, even achieving three or more ideal CVH factors were associated with lower burden of subclinical CVD, indicating the utility of this construct for disease prevention. |
| Databáze: | OpenAIRE |
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