GH and IGF-I levels and tumor shrinkage in response to first generation somatostatin receptor ligands in acromegaly: a comparative study between two reference centers for pituitary diseases in Brazil

Autor:	Leandro Kasuki, Karina Zanlorenzi Basso Manosso, Carolina Labigalini Sampaio, Mônica R. Gadelha, Ximene Antunes, Cesar Luiz Boguszewski
Rok vydání:	2021
Předmět:	Adult Male medicine.medical_specialty Endocrinology Diabetes and Metabolism Octreotide 030209 endocrinology & metabolism Ligands Lanreotide Peptides Cyclic Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Neoplasms Internal medicine Diabetes mellitus Acromegaly Adjuvant therapy Humans Medicine Receptors Somatostatin Insulin-Like Growth Factor I Human Growth Hormone business.industry Somatostatin receptor Tumor shrinkage Middle Aged medicine.disease First generation Treatment Outcome chemistry 030220 oncology & carcinogenesis Female Somatostatin business Brazil medicine.drug
Zdroj:	Endocrine. 74:146-154
ISSN:	1559-0100 1355-008X
DOI:	10.1007/s12020-021-02766-2
Popis:	To compare biochemical and tumor response rates between two reference centers for pituitary diseases in Brazil after primary and adjuvant therapy with somatostatin receptor ligands (SRL) in acromegaly. Patients were classified as non-responders (NR), partial responders (PR), and full responders (FR) to 12-month SRL therapy according to: [criteria A] normal IGF-I and random GH (rGH)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18df70b0db009196c45aa0729a83427 https://doi.org/10.1007/s12020-021-02766-2 Zobrazit plný text záznamu Full text from SpringerLink