Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44-/- tumor cells, MEFs and macrophages

Autor: Schultz, K., Schultz, Kristin, Grieger, Christina, Li, Yong, Urbánek, Pavel, Ruschel, Anne, Minnich, Kerstin, Bruder, Dunja, Gereke, Marcus, Sechi, Antonio, Herrlich, Peter
Přispěvatelé: HZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0301 basic medicine
Transcription
Genetic

Molecular biology
Physiology
Gene Expression
Nitric Oxide Synthase Type II
Pathology and Laboratory Medicine
Receptor tyrosine kinase
White Blood Cells
Mice
0302 clinical medicine
Transcription (biology)
Animal Cells
Immune Physiology
Medicine and Health Sciences
Immune Response
Melanoma
Genetic Interference
Cells
Cultured

Innate Immune System
Multidisciplinary
biology
Chemistry
Nuclear Proteins
Cell Differentiation
Cell biology
Bacterial Pathogens
Up-Regulation
RNA isolation
Hyaluronan Receptors
Medical Microbiology
030220 oncology & carcinogenesis
Cytokines
Medicine
Cellular Types
Pathogens
Research Article
Immune Cells
Science
Immunology
Diamines
Biomolecular isolation
Microbiology
03 medical and health sciences
Interferon-gamma
Immune system
Genetics
Animals
Humans
Gene Regulation
Gene
Microbial Pathogens
Gamma secretase
Innate immune system
Blood Cells
IFI16
Macrophages
CD44
Biology and Life Sciences
Cell Biology
Interferon-beta
Molecular Development
Fibroblasts
Listeria Monocytogenes
Phosphoproteins
Immunity
Innate

Research and analysis methods
Thiazoles
030104 developmental biology
Molecular biology techniques
Mutagenesis
Immune System
biology.protein
Amyloid Precursor Protein Secretases
Developmental Biology
Zdroj: PLoS ONE, Vol 13, Iss 12, p e0207358 (2018)
PLOS ONE 13(12), e0207358 (2018). doi:10.1371/journal.pone.0207358
PLoS ONE
ISSN: 1932-6203
Popis: PLOS ONE 13(12), e0207358 (2018). doi:10.1371/journal.pone.0207358
Published by PLOS, San Francisco, California, US
Databáze: OpenAIRE
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