Immediate clinical and haemodynamic benefits of restoration of pulmonary valvar competence in patients with pulmonary hypertension
| Autor: | P. Bonhoeffer, Ingram Schulze-Neick, Andrew M. Taylor, Louise Coats, Johannes Nordmeyer, Phillip Lurz |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Heart Defects Congenital Male medicine.medical_specialty Adolescent Heart disease Hypertension Pulmonary medicine.medical_treatment Blood Pressure Pulmonary Artery Young Adult medicine.artery Internal medicine medicine Humans Minimally Invasive Surgical Procedures Child Cardiac catheterization Heart Valve Prosthesis Implantation Pulmonary Valve Lung business.industry Respiratory disease Stroke volume medicine.disease Pulmonary hypertension Pulmonary Valve Insufficiency Radiography Treatment Outcome medicine.anatomical_structure Pulmonary artery Circulatory system Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Heart. 95:646-650 |
| ISSN: | 1355-6037 |
| Popis: | Objective: To analyse the potential benefit of restoration of pulmonary valvar competence in patients with severe pulmonary regurgitation (PR) and pulmonary hypertension (PH) associated with congenital heart disease. Design: Retrospective study. Setting: Tertiary paediatric and adult congenital heart cardiac centre. Interventions: Percutaneous pulmonary valve implantation (PPVI). Patients: All patients who underwent PPVI for treatment of PR in the presence of PH (mean PAP >25 mm Hg). Results: Seven patients with severe PH as a result of congenital heart disease and severe PR underwent PPVI. The valve implantation procedure was feasible and uncomplicated in all seven cases, successfully abolishing PR. There was a significant increase in diastolic (15.4 (7.3) to 34.0 (8.5) mm Hg; p = 0.007) and mean (29.7 (8.1) to 41.3 (12.9) mm Hg; p = 0.034) pulmonary artery pressures, and an improvement in NYHA functional class (from median IV to median III; p |
| Databáze: | OpenAIRE |
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