Frequency, Severity, and Duration of Autonomic Symptoms in Patients of Prodromal Dementia with Lewy Bodies

Autor:	Shuai, Liu, Chunyan, Liu, Wenzheng, Hu, Yong, Ji
Rok vydání:	2022
Předmět:	Lewy Body Disease Psychiatry and Mental health Clinical Psychology Early Diagnosis Alzheimer Disease General Neuroscience Humans Prodromal Symptoms Cognitive Dysfunction Lewy Bodies General Medicine Geriatrics and Gerontology
Zdroj:	Journal of Alzheimer's Disease. 89:923-929
ISSN:	1875-8908 1387-2877
DOI:	10.3233/jad-220275
Popis:	Background: Autonomic dysfunction is supportive clinical feature for diagnosis of prodromal dementia with Lewy bodies (DLB). Objective: To compare the features of autonomic symptoms in patients with mild cognitive impairment (MCI) due to Lewy bodies (MCI-LB) and Alzheimer’s disease (MCI-AD). Methods: Autonomic symptoms were evaluated in the MCI-LB and MCI-AD patients using the Scales for Outcomes in Parkinson’s disease for autonomic symptoms (SCOPA-AUT). Results: Thirty patients with MCI-LB and 90 patients with MCI-AD were recruited. The frequency of autonomic dysfunction was higher in patients with MCI-LB compared to the MCI-AD patients (80% versus 54.4%, p = 0.013) and the gastrointestinal symptoms were predominant (73.3% versus 35.6%, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c178ccaa08b81c30927822b2d1a93d05 https://doi.org/10.3233/jad-220275 Zobrazit plný text záznamu