Bone and metal: an orthopaedic perspective on osseointegration of metals
| Autor: | Vitali Goriainov, Richard O.C. Oreffo, Jeremy M. Latham, Richard Cook, Douglas G. Dunlop |
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| Rok vydání: | 2014 |
| Předmět: |
Aging
Materials science business.industry Orthopedic Equipment Implant design Biomedical Engineering Dentistry General Medicine Prostheses and Implants Biochemistry Osseointegration Internal Fixators Biomaterials Metals Orthopaedic procedures Animals Humans Implant Clinical case business Molecular Biology Biotechnology |
| Zdroj: | Acta biomaterialia. 10(10) |
| ISSN: | 1878-7568 |
| Popis: | The area of implant osseointegration is of major importance, given the predicted significant rise in the number of orthopaedic procedures and an increasingly ageing population. Osseointegration is a complex process involving a number of distinct mechanisms affected by the implant bulk properties and surface characteristics. Our understanding and ability to modify these mechanisms through alterations in implant design is continuously expanding. The following review considers the main aspects of material and surface alterations in metal implants, and the extent of their subsequent influence on osseointegration. Clinically, osseointegration results in asymptomatic stable durable fixation of orthopaedic implants. The complexity of achieving this outcome through incorporation and balance of contributory factors is highlighted through a clinical case report. |
| Databáze: | OpenAIRE |
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