Occupational exposure to organic solvents and risk of male breast cancer: a European multicenter case-control study
| Autor: | Lorenzo Richiardi, Diane Cyr, Wolfgang Ahrens, Elsebeth Lynge, Franco Merletti, Nasser Laouali, Monica Neri, Linda Kaerlev, Mikael Eriksson, Corinne Pilorget, María Morales-Suárez-Varela, Noemia Afonso, Giuseppe Gorini, Karl-Heinz Jöckel, Pascal Guénel, Agustin Llopis-González, Jørn Olsen, Svend Sabroe |
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| Přispěvatelé: | Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement (UMRESTTE UMR T9405), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR), Population-based Epidemiologic Cohorts Unit, Inserm, Villejuif, France, parent, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark, Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark, Occupational & Environmental Epidemiology Section, Cancer Research & Prevention Institute (ISPO), Florence, Italy, Department of Medical Sciences [Turin, Italy] (DMS), Università degli studi di Torino = University of Turin (UNITO), Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia, Burjassot, Valencia, Spain, CIBER de Epidemiología y Salud Pública (CIBERESP), Institute for Prevention Research and Epidemiology, BIPS-Institute for Epidemiology and Prevention Research GmbH, Bremen, Germany, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany, Centro Hospitalar do Porto, Porto, Portugal, Department of Oncology, Skane University Hospital, Lund, Sweden, Skane University Hospital [Lund], Department of Public Health, University of Copenhagen, Copenhagen, Denmark, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), University of Turin |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
european BENZENE trichloroethylene Medizin Cumulative Exposure ethylene glycol male breast cancer jem benzene 0302 clinical medicine Risk Factors Surveys and Questionnaires multicenter case-control study POPULATION Incidence Incidence (epidemiology) WOMEN WORKERS job-exposure matrix Middle Aged 030210 environmental & occupational health 3. Good health Europe Occupational Diseases Occupational Diseases/chemically induced Solvents/toxicity 030220 oncology & carcinogenesis Male breast cancer organic solvent petroleum solvent Public aspects of medicine RA1-1270 Adult medicine.medical_specialty Ethylene Glycol/toxicity TRICHLOROETHYLENE case-control study Job-exposure matrix ENDOCRINE-DISRUPTING CHEMICALS chlorinated solvent Trichloroethylene/toxicity Breast Neoplasms Male Europe/epidemiology 03 medical and health sciences Breast cancer breast cancer Internal medicine medicine Humans COHORT Benzene/toxicity Retrospective Studies Aged business.industry ETHYLENE-GLYCOL ETHERS MORTALITY Occupational Exposure/adverse effects Public Health Environmental and Occupational Health Case-control study OXIDE Retrospective cohort study Odds ratio occupational exposure Breast Neoplasms Male/chemically induced medicine.disease JEM Logistic Models Case-Control Studies alcoholic solvent Solvents [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business |
| Zdroj: | Scandinavian Journal of Work, Environment & Health, Vol 44, Iss 3, Pp 310-322 (2018) Scandinavian Journal of Work, Environment and Health Scandinavian Journal of Work, Environment and Health, Nordic Association of Occupational Safety and Health (NOROSH), 2018, 44 (3), pp. 310-322. ⟨10.5271/sjweh.3717⟩ Laouali, N, Pilorget, C, Cyr, D, Neri, M, Kaerlev, L, Sabroe, S, Gorini, G, Richiardi, L, Morales-Suárez-Varela, M, Llopis-Gonzalez, A, Ahrens, W, Jöckel, K-H, Afonso, N, Eriksson, M, Merletti, F, Olsen, J, Lynge, E & Guénel, P 2018, ' Occupational exposure to organic solvents and risk of male breast cancer : a European multicenter case-control study ', Scandinavian Journal of Work, Environment & Health, vol. 44, no. 3, pp. 312-322 . https://doi.org/10.5271/sjweh.3717 Laouali, N, Pilorget, C, Cyr, D, Neri, M, Kaerlev, L, Sabroe, S, Gorini, G, Richiardi, L, Morales-Suárez-Varela, M, Llopis-Gonzalez, A, Ahrens, W, Jöckel, K H, Afonso, N, Eriksson, M, Merletti, F, Olsen, J, Lynge, E & Guénel, P 2018, ' Occupational exposure to organic solvents and risk of male breast cancer : A European multicenter case-control study ', Scandinavian Journal of Work, Environment and Health, vol. 44, no. 3, pp. 310-322 . https://doi.org/10.5271/sjweh.3717 |
| ISSN: | 0355-3140 |
| DOI: | 10.5271/sjweh.3717⟩ |
| Popis: | Objectives The etiology of male breast cancer (MBC) is largely unknown but a causal role of exposure to organic solvents has been suggested. Previous studies on occupational risk factors of breast cancer were often restricted to women who are frequently exposed to lower levels and at a lower frequency than men. We investigated the association between MBC and occupational exposure to petroleum and oxygenated and chlorinated solvents in a multicenter case-control study of rare cancers in Europe. Methods The study included 104 MBC cases and 1901 controls. Detailed lifetime work history was obtained during interviews, together with sociodemographic characteristics, medical history and lifestyle factors. Occupational exposures to solvents were estimated from a job-exposure matrix. Odds ratios (OR) and their 95% confidence intervals (CI) were calculated using unconditional logistic regression models. Results Lifetime cumulative exposure to trichloroethylene >23.9 ppm years was associated with an increased MBC risk, compared to non-exposure [OR (95% CI): 2.1 (1.2-4.0); P trend |
| Databáze: | OpenAIRE |
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