Pregnancy outcomes of HIV-positive women in a tertiary centre in the UK
| Autor: | E. M. Carlin, J. E. Garley, M. Pammi |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Anti-HIV Agents Transmission rate Human immunodeficiency virus (HIV) Gestational Age medicine.disease_cause Plasma viral load Tertiary Care Centers Young Adult Pregnancy Antiretroviral Therapy Highly Active HIV Seropositivity medicine Humans Pregnancy Complications Infectious Hiv transmission Pregnancy outcomes Retrospective Studies Fetus Obstetrics business.industry Obstetrics and Gynecology Viral Load Antiretroviral therapy Infectious Disease Transmission Vertical United Kingdom Surgery Female business Viral load |
| Zdroj: | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. 35(2) |
| ISSN: | 1364-6893 |
| Popis: | With the advent of highly active antiretroviral therapy (HAART), the mother-to-child HIV transmission rate in the UK has reduced to less than 2%. A review of delivery outcomes of 106 HIV-positive pregnant women in a tertiary centre between January 2005 and December 2010 was conducted. A total of 20 women had detectable plasma viral load at 36 weeks, or before in the two women who delivered preterm. Various peripartum management measures were undertaken in women with detectable viral load close to delivery, to accelerate reduction in plasma viral load and to reduce the risk of HIV transmission to the fetus. In our review, the overall mother-to-child transmission rate was less than 1% and in women with undetectable viral load at 36 weeks, it was 0% (zero), which signifies the importance of strict virological control and a multidisciplinary approach, which plays an important role in the successful achievement of this. |
| Databáze: | OpenAIRE |
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