Synthesis and function of isopentenyl adenosine derivatives in tRNA

Autor:	Ó. Ólafsson, Britt C. Persson, B. Esberg, Glenn R. Björk
Rok vydání:	1994
Předmět:	Adenosine Stereochemistry food and beverages RNA Translation (biology) Context (language use) General Medicine Metabolism Biology biology.organism_classification Biochemistry Metabolic pathway RNA Transfer Transfer RNA medicine Bacteria medicine.drug
Zdroj:	Biochimie. 76:1152-1160
ISSN:	0300-9084
DOI:	10.1016/0300-9084(94)90044-2
Popis:	Isopentenyl adenosine derivatives can be found next to the anticodon (position 37) in tRNA from both the Bacteria and Eucarya domains. These modified nucleosides improve the efficiency of tRNA in translation, can increase and decrease translational fidelity, and make the tRNA less codon context sensitive. In bacteria the synthesis of isopentenyl adenosine derivatives seems to be linked to iron metabolism and central metabolic pathways.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15de26538e4e259403bcfb0e7cb7710 https://doi.org/10.1016/0300-9084(94)90044-2 Zobrazit plný text záznamu