Autor: |
James E, Peterman, Ross, Arena, Jonathan, Myers, Philip A, Ades, Amanda R, Bonikowske, Matthew P, Harber, Susan, Marzolini, Patrick D, Savage, Ray W, Squires, Carl J, Lavie, Leonard A, Kaminsky |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Journal of Cardiopulmonary Rehabilitation and Prevention. 43:115-121 |
ISSN: |
1932-7501 |
DOI: |
10.1097/hcr.0000000000000722 |
Popis: |
Nonexercise predictions of peak oxygen uptake (V˙o2peak) are used clinically, yet current equations were developed from cohorts of apparently healthy individuals and may not be applicable to individuals with cardiovascular disease (CVD). Our purpose was to develop a CVD-specific nonexercise prediction equation for V˙o2peak.Participants were from the Fitness Registry and Importance of Exercise International Database (FRIEND) with a diagnosis of coronary artery bypass surgery (CABG), myocardial infarction (MI), percutaneous coronary intervention (PCI), or heart failure (HF) who met maximal effort criteria during a cardiopulmonary exercise test (n = 15 997; 83% male; age 63.1 ± 10.4 yr). The cohort was split into development (n = 12 798) and validation groups (n = 3199). The prediction equation was developed using regression analysis and compared with a previous equation developed on a healthy cohort.Age, sex, height, weight, exercise mode, and CVD diagnosis were all significant predictors of V˙o2peak. The regression equation was:V˙o2peak (mL · kg-1 · min-1) = 16.18 - (0.22 × age [yr]) + (3.63 × sex [male = 1; female = 0]) + (0.14 × height [cm]) - (0.12 × weight [kg]) + (3.62 × mode [treadmill = 1; cycle = 0]) - (2.70 × CABG [yes = 1, no = 0]) - (0.31 × MI [yes = 1, no = 0]) + (0.37 × PCI [yes = 1, no = 0]) - (4.47 × HF [yes = 1, no = 0]). Adjusted R2 = 0.43; SEE = 4.75 mL · kg-1 · min-1.Compared with measured V˙o2peak in the validation group, percent predicted V˙o2peak was 141% for the healthy cohort equation and 100% for the CVD-specific equation.The new equation for individuals with CVD had lower error between measured and predicted V˙o2peak than the healthy cohort equation, suggesting population-specific equations are needed for predicting V˙o2peak; however, errors associated with nonexercise prediction equations suggest V˙o2peak should be directly measured whenever feasible. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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