Determination of salicylic acid content in pharmaceuticals using chitosan@Fe3O4/CPE electrode detected by SWV technique

Autor:	Sudarut Pitakrut, Phetlada Sanchayanukun, Sasithorn Muncharoen
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Salicylic acid magnetite nanoparticles wart treatment drugs Chemistry (miscellaneous) Medicine (miscellaneous) Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics
Zdroj:	ADMET and DMPK Volume 11 Issue 2
ISSN:	1848-7718
Popis:	Chitosan-coated magnetite nanoparticles (Chitosan@Fe3O4) used to modify on the carbon paste electrode (Chitosan@Fe3O4/CPE) for enhance sensitivity for salicylic acid (SA) analysis using square wave voltammetry (SWV) was developed in this work. The performance and behaviour of the purposed electrodes using cyclic voltammetry (CV) were investigated. The results showed that the mixed behaviour process was observed. Furthermore, parameters affecting SWV were also studied. It was discovered that the optimum conditions were two-linearity range of SA determination of 1-100 and 100-400 µM. Limits of detection (LOD) and limits of quantitation (LOQ) for SA are 0.57 µM and 0.90 µM, respectively. The proposed electrodes were successfully used to determine SA in applications employing pharmaceutical samples.
Databáze:	OpenAIRE
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