A study of increased levels of soluble vascular cell adhesion molecule-1 (SVCAM-1) in the cerebrospinal fluid of patients with multiple sclerosis and systemic lupus erythematosus
| Autor: | Teréz Pozsonyi, K. Nékám, Z. Balogh, Mariann Szongoth, A. Megyeri, Lajos Jakab, Krisztina Baraczka |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Systemic disease Multiple Sclerosis Adolescent Vascular Cell Adhesion Molecule-1 Enzyme-Linked Immunosorbent Assay Sensitivity and Specificity Central nervous system disease Cerebrospinal fluid immune system diseases medicine Humans Lupus Erythematosus Systemic Longitudinal Studies skin and connective tissue diseases Aged Lupus erythematosus business.industry Cell adhesion molecule Multiple sclerosis General Medicine Middle Aged medicine.disease Connective tissue disease Neurology Immunology Female Neurology (clinical) business Soluble Vascular Cell Adhesion Molecule 1 |
| Zdroj: | Acta Neurologica Scandinavica. 99:95-99 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1999.tb00664.x |
| Popis: | The concentration of soluble vascular cell adhesion molecules (sVCAM-1) of serum and cerebrospinal fluid (CSF) was measured in clinically selected multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients, using an ELISA assay. The mean sVCAM-1 concentration in the serum of SLE patients was higher than normal. The mean CSF sVCAM-1 concentration was increased in the MS as in the SLE group. On analysis, the data suggests that there are some similarities in the immunological effects of these two different diseases of the central nervous system. A longitudinal analysis of the CSF is requested. |
| Databáze: | OpenAIRE |
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