Mini-fluid challenge can predict arterial pressure response to volume expansion in spontaneously breathing patients under spinal anaesthesia
| Autor: | Kévin Deleporte, S. Petiot, Eugénie Bernard, Pierre-Grégoire Guinot, Emmanuel Lorne, Hervé Dupont |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Cardiac output Plasma Substitutes Hemodynamics Blood volume Critical Care and Intensive Care Medicine Anesthesia Spinal Cardiography Impedance medicine Humans Arterial Pressure Orthopedic Procedures Prospective Studies Aged Blood Volume medicine.diagnostic_test business.industry Respiration Crystalloid Solutions General Medicine Stroke volume Middle Aged Impedance cardiography Anesthesiology and Pain Medicine Blood pressure ROC Curve Volume (thermodynamics) Anesthesia Breathing Female Isotonic Solutions business |
| Zdroj: | Anaesthesia Critical Care & Pain Medicine. 34:333-337 |
| ISSN: | 2352-5568 |
| Popis: | The objective of this study was to test whether stroke volume (SV) variations in response to a fixed mini-fluid challenge (ΔSV100) measured by impedance cardiography (ICG) could predict an increase in arterial pressure with volume expansion in spontaneously breathing patients under spinal anaesthesia.Thirty-four patients, monitored by ICG who required intravenous fluid to expand their circulating volume during surgery under spinal anaesthesia, were studied. Haemodynamic variables and bioimpedance indices (blood pressure, SV, cardiac output [CO]) were measured before and after fluid challenge with 100mL of crystalloid, and before/after volume expansion. Responders were defined by ≥15% increase in systolic arterial pressure (SAP) after infusion of 500 mL of crystalloid solution.SAP increased by ≥15% in 20 (59%) of the 34 patients. SAP, SV, and CO increased and HR decreased only in responders. SV variations in response to mini-fluid challenge and volume expansion differed between patients who showed arterial responsiveness and those in whom SAP did not increase with volume expansion (11.6% [9.1-19.3] versus 2.5% [1.3-7], P0.001, and 22.4% [11.7-36.6] versus 0.9 [0-5.5], P0.001, respectively). ΔSV100 predicted an increase of arterial pressure with an area under the receiver operating characteristic (AUC) curve of 0.89 (CI95%: 0.73-0.97, P0.001). The cut-off was 5%. Baseline SAP and HR were not predictive of arterial responsiveness (P0.05).A ΔSV100 over 5% accurately predicted arterial pressure response to volume expansion during surgery. |
| Databáze: | OpenAIRE |
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