Default mode network activity in bipolar disorder
| Autor: | Eleonora Maggioni, Pietro Bontempi, Niccolò Zovetti, Cinzia Perlini, Maria Gloria Rossetti, Marcella Bellani, Paolo Brambilla |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Bipolar Disorder
Epidemiology review Epidemiology for Behavioural Neurosciences 03 medical and health sciences default mode network 0302 clinical medicine Neural Pathways medicine Humans Bipolar disorder Default mode network Brain Mapping Resting state fMRI medicine.diagnostic_test business.industry Public Health Environmental and Occupational Health Brain medicine.disease Magnetic Resonance Imaging 030227 psychiatry bipolar disorder resting-state fMRI Psychiatry and Mental health Posterior cingulate Healthy individuals Nerve Net business Functional magnetic resonance imaging Neuroscience human activities 030217 neurology & neurosurgery |
| Zdroj: | Epidemiology and Psychiatric Sciences |
| ISSN: | 2045-7979 2045-7960 |
| Popis: | Since its discovery in 1997, the default mode network (DMN) and its components have been extensively studied in both healthy individuals and psychiatric patients. Several studies have investigated possible DMN alterations in specific mental conditions such as bipolar disorder (BD). In this review, we describe current evidence from resting-state functional magnetic resonance imaging studies with the aim to understand possible changes in the functioning of the DMN in BD. Overall, several types of analyses including seed-based and independent component have been conducted on heterogeneous groups of patients highlighting different results. Despite the differences, findings seem to indicate that BD is associated with alterations in both frontal and posterior DMN structures, mainly in the prefrontal, posterior cingulate and inferior parietal cortices. We conclude this review by suggesting possible future research directions. |
| Databáze: | OpenAIRE |
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