[Reduction in necrotising enterocolitis after implementing an evidence-based enteral nutrition protocol in very low birth weight newborns]

Autor: María González López, Tomás Sánchez-Tamayo, María Concepción Moreno Algarra, María Gracia Espinosa Fernández, Laura Affumicato, Verónica Fernández Romero, Enrique Salguero García
Rok vydání: 2015
Předmět:
Zdroj: Anales de Pediatría (English Edition), Vol 85, Iss 6, Pp 291-299 (2016)
ISSN: 1695-9531
Popis: Introduction: An unexpected increase in the incidence of necrotising enterocolitis (NEC) cases was observed in our hospital. Just in case, our feeding policy could be responsible, it was decided to conduct a systematic review and develop a clinical guideline regarding enteral nutrition of very low birth weight infants (VLBW). Objective: To assess the impact of the new feeding protocol in the incidence of NEC. Method: A “before” (2011) and “after” (May 2012–April 2013) study was performed on the new feeding protocol. This included initiation of enteral feeding in the absence of haemodynamic problems, a trophic feeding period of 5–7 days, and subsequent increments of 20–30 mL/kg/day, of breast milk/donor human milk from the beginning. Probiotics were not administered. Primary outcome: incidence of NEC II 2 Bell's stage. Secondary outcomes: focal intestinal perforation, overall mortality and mortality due to NEC, nosocomial sepsis; weight at 28 days and 36 weeks; % of infants with weight p
Databáze: OpenAIRE