Disseminated histoplasmosis in a patient with HIV diagnosed by simple bedside investigations
Autor: | Wannarat Pongpirul, Patama Suttha, Pongsakorn Buraphat |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Tuberculosis Antifungal Agents Itraconazole 030106 microbiology Physical examination HIV Infections Histoplasmosis Article Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Amphotericin B medicine Humans 030212 general & internal medicine medicine.diagnostic_test business.industry General Medicine medicine.disease Rash Surgery Anti-Bacterial Agents Bone marrow examination Female Differential diagnosis medicine.symptom business Chest radiograph medicine.drug |
Zdroj: | BMJ case reports. 2017 |
ISSN: | 1757-790X |
Popis: | A 41-year-old HIV-infected woman presented with prolonged fever at another hospital. Besides low CD4 count (8 cell/mm3) and pancytopaenia, blood cultures, chest radiograph, chest–whole abdominal CT and bone marrow examination were unremarkable. Empirical treatment for tuberculosis was given. One week later, she developed rash and was transferred to our hospital. Physical examination showed multiple pruritic erythematous purplish maculopapular rashes with central necrotic areas predominantly on face, back-chest wall and both forearms (figure 1). Peripheral blood smear (figure 2) and skin scraping (figure 3) revealed multiple intracellular yeast-like organisms suggestive of Histoplasma capsulatum . Intravenous amphotericin B was given, followed by oral itraconazole. … |
Databáze: | OpenAIRE |
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