Results of a 2‐year lifestyle intervention for type 2 diabetes: the Reach Ahead for Lifestyle and Health ‐Diabetes randomized controlled trial

Autor: Deborah J. Wexler, Yuchiao Chang, Douglas E. Levy, Bianca Porneala, Jeanna McCarthy, Anthony Rodriguez Romero, Valerie Goldman, Paul M. Copeland, Jeanne Steppel‐Reznik, Linda M. Delahanty
Rok vydání: 2022
Předmět:
Zdroj: Obesity. 30:1938-1950
ISSN: 1930-739X
1930-7381
Popis: The Reach Ahead for Lifestyle and Health (REAL HEALTH)-Diabetes study assessed the comparative effectiveness of two Look AHEAD (Action for Health in Diabetes)-adapted lifestyle intervention (LI) arms targeting weight loss in type 2 diabetes compared with medical nutrition therapy (MNT) referral. At 1 year, LI had greater weight loss than MNT. This study reports outcomes at 24 (end of LI) and 36 months.Participants (N = 211) with type 2 diabetes and BMI 25 kg/mParticipants were 61.7 (SD 10.2) years old; 55% were female; 77% were non-Hispanic White; and had mean (SD) weight of 98 (18.9) kg and mean (SD) HbA1c of 7.7% (1.2%). Mean (SD) weight change at 24 and 36 months was -4.4% (5.9%) and -4.4% (5.4%) in in-person LI, -4.0% (5.8%) and -5.3% (6.4%) in telephone LI, and -3.1% (5.2%) and -5.8% (7.1%) in MNT, with no statistically significant difference in weight or HbA1c at 24 and 36 months. Compared with MNT, LI arms had favorable changes in patient-reported outcomes related to learned dietary skills.There were no differences in weight outcomes among LI participants compared with referral to MNT at the end of intervention or 1 year after its conclusion.
Databáze: OpenAIRE