Prevalence and Persistence of Antimicrobial Resistance in Broiler Indicator Bacteria
| Autor: | Lieve Herman, Davy Persoons, Freddy Haesebrouck, Patrick Butaye, Marc Heyndrickx, Boudewijn Catry, Annemieke Smet, An Martel, Jeroen Dewulf |
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| Rok vydání: | 2010 |
| Předmět: |
Microbiology (medical)
Nalidixic acid animal diseases medicine.medical_treatment Enterococcus faecium Immunology Dalfopristin Microbial Sensitivity Tests Drug resistance Microbiology Antibiotic resistance Drug Resistance Multiple Bacterial Escherichia coli Prevalence medicine Animals Poultry Products Escherichia coli Infections Gram-Positive Bacterial Infections Pharmacology biology Bird Diseases Quinupristin biochemical phenomena metabolism and nutrition Antimicrobial biology.organism_classification Anti-Bacterial Agents Multiple drug resistance Food Microbiology Chickens medicine.drug |
| Zdroj: | Microbial Drug Resistance. 16:67-74 |
| ISSN: | 1931-8448 1076-6294 |
| Popis: | This study explored the prevalence and persistence of acquired antimicrobial resistance in Escherichia coli and Enterococcus faecium from healthy broilers. In 32 broiler farms, cloacal samples were taken during two production rounds, with one production round in between. For 10 of the sampled flocks, samples from the carcasses at the slaughterhouse were also collected. For E. coli, high levels of resistance were found for ampicillin, nalidixic acid, streptomycin, tetracycline, and the combination of trimethoprim and sulfonamide. Over 58% of all the isolates showed resistance to four or more antimicrobial agents. Only 4.8% were fully susceptible for all 14 drugs tested. A remarkably high resistance rate (up to 41%) to ceftiofur was found. The enterococci were frequently resistant to macrolides, tetracycline, and the combination quinopristin/dalfopristin. Over 80% displayed acquired resistance to four or more antimicrobial agents, and 3.9% were fully susceptible for the eight agents tested. Resistance was found to persist over consecutive production rounds. There was a good correlation between results obtained with cloacal samples of the live animals and caecal content samples collected in the slaughterhouse for both E. coli and E. faecium. For E. coli but not for E. faecium, the resistance profile of neck skin isolates was different from that of cloacal isolates. |
| Databáze: | OpenAIRE |
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