Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease

Autor: Linda S. de Vries, Nathalie H.P. Claessens, Selma O. Algra, Felix Haas, Manon J.N.L. Benders, Renske Schappin, Maria J. C. Eijsermans, Tom L. Ouwehand, Nicolaas J.G. Jansen
Přispěvatelé: Academic Medical Center, ACS - Heart failure & arrhythmias, ACS - Atherosclerosis & ischemic syndromes
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Heart Defects
Congenital
Male
Pediatrics
medicine.medical_specialty
Internal capsule
Heart disease
Intelligence
Clinical Neurology
Neuropsychological Tests
03 medical and health sciences
0302 clinical medicine
Child Development
Developmental Neuroscience
Internal Capsule
030225 pediatrics
medicine
Humans
Pediatrics
Perinatology
and Child Health
Toddler
Critical congenital heart disease
Cardiac Surgical Procedures
Child Behavior Checklist
Child
Wechsler Preschool and Primary Scale of Intelligence
business.industry
Infant
Newborn
Wechsler Scales
Wechsler Adult Intelligence Scale
Perioperative
medicine.disease
Perinatology
and Child Health
Neurodevelopmental Disorders
Brain Injuries
Child
Preschool
Pediatrics
Perinatology and Child Health
Female
Neurology (clinical)
business
030217 neurology & neurosurgery
Follow-Up Studies
Zdroj: Developmental Medicine and Child Neurology, 60(10), 1052. Wiley-Blackwell
Developmental medicine and child neurology, 60(10), 1052-1058. Wiley-Blackwell
ISSN: 0012-1622
Popis: Aim: To assess the impact of perioperative neonatal brain injury and brain volumes on neurodevelopment throughout school-age children with critical congenital heart disease (CHD). Method: Thirty-four survivors of neonatal cardiac surgery (seven females, 27 males) were included. Neonatal preoperative and postoperative cerebral magnetic resonance imaging was performed and neurodevelopment was assessed at 24 months (SD 0.7, n=32, using Bayley Score of Infant and Toddler Development, Child Behavior Checklist) and 6 years (mean age 5y 11mo; SD 0.3, n=30, using Movement Assessment Battery for Children, Wechsler Preschool and Primary Scale of Intelligence, Child Behavior Checklist, Teacher Report Form). Brain injury, brain volumes, and cortical measures were related to outcome with adjustment for maternal educational level. Results: Two-year cognitive score and 6-year Full-scale IQ were poorer in children with neonatal white matter injury (n=21, all p
Databáze: OpenAIRE
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