Hepatic Microwave Ablation Zone Size: Correlation with Total Energy, Net Energy, and Manufacturer-Provided Chart Predictions
| Autor: | R. Marie Koch, Stuart G. Silverman, Vincent M. Levesque, Servet Tatli, Paul J. Catalano, Paul B. Shyn, Jeffery R. Bird |
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| Rok vydání: | 2016 |
| Předmět: |
Ablation Techniques
Adult Male medicine.medical_treatment 030218 nuclear medicine & medical imaging Correlation 03 medical and health sciences 0302 clinical medicine Optics Chart Predictive Value of Tests medicine Humans Radiology Nuclear Medicine and imaging Microwaves Aged Retrospective Studies Aged 80 and over business.industry Patient Selection Microwave ablation Liver Neoplasms Middle Aged Ablation Magnetic Resonance Imaging Confidence interval Tumor Burden Treatment Outcome 030220 oncology & carcinogenesis Linear Models Female Tomography Cardiology and Cardiovascular Medicine business Nuclear medicine Tomography X-Ray Computed Ablation zone |
| Zdroj: | Journal of vascular and interventional radiology : JVIR. 27(9) |
| ISSN: | 1535-7732 |
| Popis: | Purpose To determine whether total energy (TE) reaching the microwave (MW) applicator or net energy (NE) exiting the applicator (after correcting for reflectivity) correlates better with hepatic MW ablation zone dimensions than manufacturer-provided chart predictions. Materials and Methods Single-applicator, nonoverlapping ablations of 93 liver tumors (0.7–5.9 cm) were performed in 52 adult patients. TE and NE were recorded for each ablation. Long axis diameter (LAD), short axis diameter (SAD), and volume (V) of each ablation zone were measured on magnetic resonance imaging or computed tomography after the procedure and retrospectively compared with TE; NE; and manufacturer-provided chart predictions of LAD, SAD, and V using correlation and regression analyses. Results For treated tumors, mean (± SD) TE and NE were 49.8 kJ (± 22.7) and 36.4 kJ (± 19.4). Mean LAD, SAD, and V were 5.8 cm (± 1.3), 3.7 cm (± 0.8), and 44.1 cm 3 (± 25.4). Correlation coefficients (95% confidence interval) with LAD, SAD, and V were 0.46 (0.28, 0.61), 0.52 (0.36, 0.66), and 0.52 (0.36, 0.66) for TE; 0.42 (0.24, 0.58), 0.55 (0.39, 0.68), and 0.53 (0.36, 0.66) for NE; and 0.51 (0.34, 0.65), 0.63 (0.49, 0.74), and 0.60 (0.45, 0.73) for chart predictions. Using regression analysis and controlling for TE, SAD was 0.34 cm larger in patients with cirrhosis than in patients without cirrhosis. Conclusions Correcting for reflectivity did not substantially improve correlation of energy values with MW ablation zone size parameters and did not outperform manufacturer-provided chart predictions. Correlations were moderate and variable using all methods. The results suggest a disproportionate influence of tissue factors on MW ablation results. |
| Databáze: | OpenAIRE |
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