Expression of Dipeptidylaminopeptidase-IV in Some Human T and B Cell Lines
| Autor: | Maya D. Srivastava, Arvind K. Bhargava |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
B-Lymphocytes
Leukemia Dipeptidyl Peptidase 4 T-Lymphocytes Hematology General Medicine T lymphocyte Human cell Biology medicine.disease Molecular biology Cell Line Neoplasm Proteins Lymphoma medicine.anatomical_structure Cell culture Immunology Gene expression medicine Cytochemistry Humans Lymphoma Large B-Cell Diffuse Dipeptidyl-Peptidases and Tripeptidyl-Peptidases B cell |
| Zdroj: | Acta Haematologica. 76:25-28 |
| ISSN: | 1421-9662 0001-5792 |
| DOI: | 10.1159/000206013 |
| Popis: | The specificity of the expression of dipeptidylaminopeptidase-IV (DAP-IV) was examined in cells from leukemia patients and in 33 normal and leukemic human cell lines widely used in various studies. There was no correlation between DAP-IV activity and OKT4 positivity or maturation stage in T cells. In addition, DAP-IV was unexpectedly expressed by 4 B cell lines and 1 histiocytic lymphoma cell line, indicating either lack of specificity of DAP-IV or infidelity of gene expression under unnatural culture environment. |
| Databáze: | OpenAIRE |
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