Brain 18F-FDG, 18F-Florbetaben PET/CT, 123I-FP-CIT SPECT and Cardiac 123I-MIBG Imaging for Diagnosis of a 'Cerebral Type' of Lewy Body Disease
| Autor: | Laurent Cleret de Langavant, Corentin Rabu, Emmanuel Itti, Julia Chalaye, Eva Evangelista, Ophélie Bélissant, Gilles Fénelon, Axel Van Der Gucht, Sophie Bonnot-Lours, Anne-Ségolène Cottereau |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
PET-CT
medicine.medical_specialty Pathology Lewy body business.industry Parkinsonism Case Report medicine.disease 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Neuroimaging Cortex (anatomy) Medicine Dementia Radiology Nuclear Medicine and imaging Radiology Cognitive decline business Florbetaben 030217 neurology & neurosurgery |
| Popis: | A 67-year-old man was referred for fluctuating neuropsychiatric symptoms, featuring depression, delirious episodes, recurrent visual hallucinations and catatonic syndrome associated with cognitive decline. No parkinsonism was found clinically even under neuroleptic treatment. (18)F-FDG PET/CT showed hypometabolism in the posterior associative cortex including the occipital cortex, suggesting Lewy body dementia, but (123)I-FP-CIT SPECT was normal and cardiac (123)I-MIBG imaging showed no signs of sympathetic denervation. Alzheimer's disease was excluded by a normal (18)F-florbetaben PET/CT. This report suggests a rare case of α-synucleinopathy without brainstem involvement, referred to as "cerebral type" of Lewy body disease. |
| Databáze: | OpenAIRE |
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