Correlation Between Peak Nasal Flow Reversibility and Mucociliary Clearance in Allergic Rhinitis
| Autor: | Jitanong Leelapong, Suwalee Ruttanaphol, Virat Kirtsreesakul |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Mucociliary clearance Minimal Clinically Important Difference Peak Expiratory Flow Rate Allergic inflammation Correlation 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine medicine Humans Prospective Studies 030223 otorhinolaryngology Alternative methods medicine.diagnostic_test business.industry Minimal clinically important difference Middle Aged Rhinitis Allergic Rhinomanometry Nasal Decongestants Nasal Mucosa Cross-Sectional Studies Otorhinolaryngology Mucociliary Clearance 030220 oncology & carcinogenesis Cardiology Nasal airflow Female business Inspiratory Capacity Nasal symptoms |
| Zdroj: | The LaryngoscopeBIBLIOGRAPHY. 130(6) |
| ISSN: | 1531-4995 |
| Popis: | OBJECTIVES/HYPOTHESIS Reversibility of nasal airflow after decongestion measured by rhinomanometry is associated with the severity of allergic inflammation. Peak nasal flow is a simpler alternative method for assessing nasal patency. The aim of this study was to evaluate the correlation between changes in peak nasal expiratory and inspiratory flows (PNEFs and PNIFs) after decongestion and nasal mucociliary clearance times (NMCCTs). STUDY DESIGN Single-center, prospective cross-sectional study. METHODS One hundred one allergic rhinitis patients were enrolled. Nasal symptoms and NMCCTs were assessed. PNEF and PNIF were performed before and after decongestion. Correlations between changes in PNEF and PNIF after decongestion and NMCCTs were analyzed. One-half the standard deviation of baseline peak nasal flows was used to estimate the minimal clinically important differences (MCIDs) and discriminate between patients with reversible mucosa and with irreversible mucosa. RESULTS PNEF showed more peak flow improvements after decongestion compared to PNIF. Changes in PNEF had better negative correlations with NMCCTs than PNIF (ρ = -0.49, P |
| Databáze: | OpenAIRE |
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