Lobular breast carcinoma with colonic metastases: A synchronous diagnosis in a 4-day period
| Autor: | Joan Martínez-Orfila, Ivonne Vázquez‐de las Heras, Mar Iglesias-Coma, Raquel Albero-González, Javier Gimeno-Beltrán, Agustín Seoane-Urgorri, Dolores Naranjo-Hans, Francesc Alameda‐Quitllet, Josep Maria Corominas |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Lobular carcinoma Lobular Breast Carcinoma Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Breast cancer Metastatic Lobular Breast Carcinoma Cancer screening lcsh:Pathology Micropolyps Synchronous diagnosis medicine Mammography Colonic metastasis skin and connective tissue diseases medicine.diagnostic_test business.industry medicine.disease Metastatic breast cancer Còlon -- Càncer 030220 oncology & carcinogenesis Invasive lobular carcinoma Mama -- Càncer 030211 gastroenterology & hepatology business lcsh:RB1-214 |
| Zdroj: | Human Pathology: Case Reports, Vol 7, Iss, Pp 27-30 (2017) |
| Popis: | Lobular breast carcinoma involving the colon is a rare condition. In most cases reported in the literature, metastases are detected after a 20-year latency period after the initial diagnosis. Here we describe a case in which metastatic lobular breast carcinoma and colonic metastasis were simultaneously diagnosed—with only 4 days between the two diagnoses. A 55-year-old woman underwent mammography and colonoscopy in the setting of the National Cancer Screening Program. A malignant nodule in the left breast was detected, and core-biopsy revealed an invasive lobular carcinoma. Simultaneously, numerous intestinal micropolyps were sampled. Histological examination of the latter showed tumor cells growing in cords and presenting signet-ring appearance, thereby confirming metastatic breast carcinoma. In cases such as the one described here, pathological diagnosis can be extremely difficult and deep biopsies are required. Metastatic breast cancer involving the colon can be considerably underestimated because of the unspecificity of the clinical manifestations, the long latency period, and diverse radiological findings that can lead to misdiagnosis. We conclude that clinicians should rule out intestinal metastasis in patients diagnosed with breast cancer, especially the lobular type, and presenting non-specific abdominal symptoms. Keywords: Lobular carcinoma, Colonic metastasis, Micropolyps, Synchronous diagnosis |
| Databáze: | OpenAIRE |
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