Case of placental insufficiency and premature delivery in a Fontan pregnancy:physiological insights and considerations on risk stratification
| Autor: | G Biglino, Johanna Trinder, Aarthi R Mohan, Brenda Kelly, Stephanie L. Curtis, Maria Victoria Ordonez, Massimo Caputo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Heart Defects
Congenital medicine.medical_specialty Placental Finding Pregnancy Complications Cardiovascular Bristol Heart Institute Magnetic Resonance Imaging Cine Placental insufficiency 030204 cardiovascular system & hematology Fontan Procedure Hypoplastic left heart syndrome Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Placenta Journal Article medicine Humans Diseases of the circulatory (Cardiovascular) system 030212 general & internal medicine Intensive care medicine Fetus imaging and diagnostics business.industry Congenital Heart Disease Infant Newborn Fontan physiology fetal Delivery Obstetric Placental Insufficiency medicine.disease medicine.anatomical_structure RC666-701 Risk stratification Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Ordonez, M V, Biglino, G, Caputo, M, Kelly, B, Mohan, A R, Trinder, J & Curtis, S L 2021, ' Case of placental insufficiency and premature delivery in a Fontan pregnancy : physiological insights and considerations on risk stratification ', Open Heart, vol. 8, no. 1, e001211 . https://doi.org/10.1136/openhrt-2019-001211 Open Heart, Vol 8, Iss 1 (2021) Ordonez, M V, Caputo, M, Biglino, G & Curtis, D S 2021, ' Case of placental insufficiency and premature delivery in a Fontan pregnancy : physiological insights and considerations on risk stratification ', Open Heart, vol. 8, no. 1, e001211 . https://doi.org/10.1136/openhrt-2019-001211 Open Heart |
| Popis: | ObjectivesThe coexistence of two complex physiologies such as Fontan and pregnancy is still not fully understood. We aim to add a unique and essential knowledge to help our colleagues in the management of Fontan patients that undergo pregnancy as well as the fetus and the placenta perfusion.Methods and resultsWe analyse the coexistence of Fontan and pregnancy physiology on a complex case of a woman with hypoplastic left heart syndrome palliated with a univentricular repair who became pregnant, delivered very prematurely and had atypical placental findings.ConclusionHistopathological analysis of the placenta could help us to refine the understanding of Fontan physiology adaptation during pregnancy, predict women and fetal outcomes as well as to plan a better pre-pregnancy status. However, further evidence is needed in order to reach a more solid and unified conclusion. |
| Databáze: | OpenAIRE |
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