Screening of acetylcholinesterase inhibitory and antioxidant active compounds from Terminalia chebula fruits by spectrum-effect relationship and liquid chromatography-mass spectrometry analysis

Autor:	Huan‐Huan Zhao, Yan‐Jun Li, Zhao‐Hui Guo, Juan Chen
Rok vydání:	2022
Předmět:	Ethanol Plant Extracts Fruit Acetylcholinesterase Terminalia Water Filtration and Separation Antioxidants Chromatography High Pressure Liquid Mass Spectrometry Analytical Chemistry Chromatography Liquid
Zdroj:	Journal of separation scienceREFERENCES. 45(18)
ISSN:	1615-9314
Popis:	Screening and identification of active components from traditional Chinese medicines is rather challenging due to the diversity and complexity of chemical components. Herein, a comprehensive strategy based on a spectrum-effect relationship model and LC-MS analysis was developed to screen active components from Terminalia chebula fruits. The water extract of T. chebula fruits was subjected to macroporous resin column and then eluted successively with water and 30%, 50%, 70%, and 95% ethanol. The 30% ethanol eluate fractions of eighteen batches from T. chebula fruits were used for the spectrum-effect relationship study. The IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e59e3f9b731f500a7091e120c4c78a https://pubmed.ncbi.nlm.nih.gov/35819997 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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