Exposure-response relationship of residential dampness and mold damage with severe lower respiratory tract infections among under-five children in Nigeria

Autor: Fakunle, Adekunle Gregory, Jafta, Nkosana, Okekunle, Akinkunmi Paul, Smit, Lidwien A M, Naidoo, Rajen N, IRAS OH Epidemiology Microbial Agents
Přispěvatelé: IRAS OH Epidemiology Microbial Agents
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Environmental Epidemiology, 7(2), 1. Wolters Kluwer
ISSN: 2474-7882
Popis: Background: Previous epidemiological studies demonstrated an increased risk of respiratory health effects in children and adults exposed to dampness or mold. This study investigated associations of quantitative indicators of indoor dampness and mold exposure with severe lower respiratory tract infections (LRTI) among children aged 1-59 months in Ibadan, Nigeria. Methods: In-home visits were conducted among 178 children hospitalized with LRTI matched by age (±3 months), sex, and geographical location with 180 community-based children without LRTI. Trained study staff evaluated the indoor environment using a standardized home walkthrough checklist and measured visible dampness and mold damage. Damp-moldy Index (DMI) was also estimated to quantify the level of exposure. Exposure-response relationships of dampness and mold exposure with severe LRTI were assessed using multivariable restricted cubic spline regression models adjusting for relevant child, housing, and environmental characteristics. Results: Severe LRTI cases were more often male than female (61.8%), and the overall mean (SD) age was 7.3 (1.35) months. Children exposed to dampness
Databáze: OpenAIRE