Mycophenolic acid for lymphomatoid papulosis
| Autor: | Scott Walsh, Trevor Champagne |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Skin Neoplasms CD30 business.industry Dermatology Prodrug Middle Aged Mycophenolic Acid medicine.disease Mycophenolate Mycophenolic acid Lymphomatoid Papulosis medicine Humans Surgery Methotrexate Female Lymphomatoid papulosis business Rapid response Immunosuppressive Agents medicine.drug |
| Zdroj: | Journal of cutaneous medicine and surgery. 17(5) |
| ISSN: | 1203-4754 |
| Popis: | Background: Lymphomatoid papulosis is a rare CD30+ lymphoproliferative T-cell disorder with limited effective treatments. Objective: We describe the case of a 50-year-old woman diagnosed with lymphomatoid papulosis who was unable to access phototherapy and who failed to clear while on systemic treatment with methotrexate. Methods: The patient was initiated on mycophenolate mofetil (MMF), a prodrug of mycophenolic acid, at a dose of 2 g divided twice daily. Results: MMF produced a rapid response with complete clearing within 8 weeks, and the patient has been successfully maintained for 2 years at the same dose with no noted side effects. Other patients in our clinic have had similar success. Conclusions: Mycophenolic acid is a safe and well-tolerated therapy for lymphomatoid papulosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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