Risk factors for nontuberculous mycobacterial isolation in patients with cystic fibrosis: A meta‐analysis
| Autor: | Raphaele Nove-Josserand, Stéphane Durupt, Pierre-Régis Burgel, Zoe Cavalli, Philippe Reix, Isabelle Durieu, Quitterie Reynaud, Romain Bricca |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Cystic Fibrosis Mycobacterium Infections Nontuberculous medicine.disease_cause Azithromycin Cystic fibrosis 03 medical and health sciences 0302 clinical medicine Risk Factors 030225 pediatrics Internal medicine Humans Medicine biology business.industry Nontuberculous Mycobacteria Odds ratio bacterial infections and mycoses biology.organism_classification medicine.disease Confidence interval Stenotrophomonas maltophilia 030228 respiratory system Staphylococcus aureus Meta-analysis Pediatrics Perinatology and Child Health Nontuberculous mycobacteria business medicine.drug |
| Zdroj: | Pediatric Pulmonology. 55:2653-2661 |
| ISSN: | 1099-0496 8755-6863 |
| Popis: | BACKGROUND To better understand the mechanisms of infection with nontuberculous mycobacteria (NTM) in patients with cystic fibrosis (CF), we explore different risk factors associated with NTM positivity in a meta-analysis. METHODS Studies published before 31 July 2019 were selected from MEDLINE. Combined odds ratios (ORs) were calculated by pooling the ORs of each study. The weighted mean difference (WMD) was used for continuous numerical measurements. Summary data were pooled using fixed- or random-effects models according to the presence of heterogeneity (P 50%). RESULTS Nineteen studies with a total of 23 418 patients, of whom 1421 (6%) were diagnosed as NTM positive, were included. Older age was significantly associated with NTM positivity (WMD = 2.12, 95% confidence interval [CI]: 1.11-3.13; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text