Study of mutagenic activity of dioxidine by the polyorgan micronuclear method
| Autor: | Sycheva Lp, S. M. Sheremet’eva, Andrey D. Durnev, M. A. Kovalenko, Zhurkov Vs |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lung Micronucleus Tests Bone Marrow Cells Epithelial Cells General Medicine Biology Molecular biology General Biochemistry Genetics and Molecular Biology Mice Inbred C57BL Mice medicine.anatomical_structure Quinoxalines Micronucleus test medicine Animals Large intestine Bone marrow Intestine Large Mutagens |
| Zdroj: | Bulletin of experimental biology and medicine. 138(2) |
| ISSN: | 0007-4888 |
| Popis: | Antibacterial preparation dioxidine administered four times in doses of 10, 100, and 300 mg/kg increased the incidence of micronucleated cells in the bone marrow, lungs, and large intestine of mice. Bone marrow cells were most sensitive, while cells of the lungs and large intestine exhibited lower sensitivity to the cytogenetic effect of dioxidine. |
| Databáze: | OpenAIRE |
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