Evaluation of quality of life and cost-effectiveness of definitive surgery and the levonorgestrel intrauterine system as treatment options for heavy menstrual bleeding
| Autor: | Fatma Kaya, Deniz Aka Satar, Cevdet Adıgüzel, Hakan Nazik, Sefa Arlier, Sevtap Seyfettinoğlu, Eda Eskimez |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Cost effectiveness Cost-Benefit Analysis Levonorgestrel Hysterectomy Young Adult 03 medical and health sciences Postoperative Complications 0302 clinical medicine Quality of life medicine Definitive surgery Humans 030212 general & internal medicine Menorrhagia Abdominal hysterectomy Obstetrics business.industry Intrauterine Devices Medicated Outcome measures Treatment options General Medicine Middle Aged Treatment Outcome Menstrual bleeding Quality of Life Cost analysis levonorgestrel-releasing intrauterine system menorrhagia surgery quality of life Female business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Volume: 47, Issue: 3 789-794 Turkish Journal of Medical Sciences |
| ISSN: | 1303-6165 1300-0144 |
| DOI: | 10.3906/sag-1512-115 |
| Popis: | Background/aim: This study aimed to compare the levonorgestrel intrauterine system (LNG-IUS) with abdominal hysterectomy (TAH) and total laparoscopic hysterectomy (TLH) as first-line treatments for heavy menstrual bleeding (HMB). Materials and methods: Ninety-eight patients aged 20-55 years who complained of regular heavy menstrual bleeding were enrolled in the study. The TAH group included 29 patients, the LNG-IUS group included 34, and the TLH group included 35. These groups were compared in terms of quality of life and the cost-effectiveness of the selected methods. Quality of life was assessed using the 36-Item Short Form (SF-36), and cost-effectiveness was assessed according to the current cost of each approach. Results: The quality of life parameters, with the exception of mental health, improved significantly in the LNG-IUS, TAH, and TLH groups. The mean costs of the LNG-IUS, TAH, and TLH procedures were $99.15 ± 4.90, $538.82 ± 193.00 and $1617.05 ± 258.44, respectively (P < 0.05). Overall, LNG-IUS was the most cost-effective treatment option. Conclusion: The outcome measures of the SF-36 revealed that after 6 months, these treatments were equal in terms of quality of life, except for mental health. LNG-IUS was the most cost-effective approach. |
| Databáze: | OpenAIRE |
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