Adjuvant Temozolomide Chemotherapy for Treatment of Papillary Tumor of the Pineal Region

Autor: Agnese Assi, Sergio M. Gaini, Rolando Campanella, Dario Bauer, Manuela Caroli, Martin Lorenzetti, C. Arienta, F. Motta
Rok vydání: 2011
Předmět:
Zdroj: World Neurosurgery. 76:160-163
ISSN: 1878-8750
DOI: 10.1016/j.wneu.2010.10.039
Popis: Background We present a personal case of papillary pineocytoma in a 42-year-old woman. Methods The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. Results Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. Conclusion Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.
Databáze: OpenAIRE