Need for analgesics/drugs of abuse: a comparison between headache patients and addicts by the Leeds Dependence Questionnaire (LDQ)
| Autor: | G Pasciullo, Arrigo F G Cicero, Alfio Bertolini, Emilio Sternieri, Sheila Leone, Anna Ferrari |
|---|---|
| Přispěvatelé: | A. Ferrari, A. Cicero, A. Bertolini, S. Leone, G. Pasciullo, E. Sternieri |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Drugs of abuse media_common.quotation_subject Analgesic 03 medical and health sciences 0302 clinical medicine Daily headache chronic daily headache LDQ Internal medicine medicine 030212 general & internal medicine media_common Analgesics drugs Substance dependence Headache epidemiology business.industry Addiction addiction analgesics medication overuse headache Headache General Medicine medicine.disease Leeds Dependence Questionnaire Anesthesia Drug addict Neurology (clinical) business 030217 neurology & neurosurgery Analgesic abuse |
| Popis: | Our aim was to compare the need for analgesics/drugs of abuse between headache patients—chronic and episodic headache sufferers—and addicts, by the Leeds Dependence Questionnaire (LDQ). This is a self-completion 10-item instrument to measure dependence upon a variety of substances. We administered the LDQ questionnaire to 122 chronic daily headache (CDH) sufferers who had been taking one dose of analgesic drug every day for at least 1 year; 71 subjects suffering from episodic headache (EH) using analgesics only occasionally; 115 consecutive drug addicts (DA) with a diagnosis of substance dependence. The mean LDQ total score was similar in the CDH (11.58 ± 6.35) and DA (10.37 ± 6.51) groups, and for both it was significantly higher than the score in the EH (5.61 ± 3.00) group ( P < 0.001). The CDH group had the highest scores, and higher scores than the DA group (Z = −8.18, P < 0.001) in item 8, assessing the primacy of effect over the kind of analgesic used, and in item 10 (Z = −5.03, P < 0.001), asking if it is difficult to live without the analgesic; the DA group had the highest scores, and higher scores than the CDH group, in item 9 (Z = −5.07, P < 0.001) addressing the need for the continued administration of the drug to maintain well-being, and in item 3 (Z =−2.39, P < 0.05), exploring compulsion to start the use of the drug. The EH group had lower scores in all items ( P < 0.05) except for item 9, where there was no difference from CDH group; the EH group had also lower scores ( P < 0.001) than the DA group, except for item 8, where, instead, the score was higher than in the DA group (Z = −5.33, P < 0.001). A strong link develops between chronic headache patients and the analgesics they use. This sort of ‘dependence’ appears to be a consequence of headache, originating from the necessity for the analgesic to cope with everyday life. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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