Emerging Co-Pathogens: New Delhi Metallo-beta-lactamase producing Enterobacterales Infections in New York City COVID-19 Patients

Autor: Priya Nori, Julian Torres-Isasiga, Philip Gialanella, Yi Guo, Marilou Corpuz, Zachary Fleischner, Wendy Szymczak, Uriel R. Felsen, Yoram A. Puius, Victor Chen, Anjali Sharma, Kelsie Cowman, Rachel Bartash
Rok vydání: 2020
Předmět:
Male
0301 basic medicine
Microbiology (medical)
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
medicine.drug_class
030106 microbiology
Antibiotics
Carbapenem-resistant enterobacteriaceae
Drug resistance
beta-Lactamases
Antimicrobial Stewardship
03 medical and health sciences
0302 clinical medicine
Enterobacteriaceae
Enterobacterales
Enterobacter cloacae
medicine
Central Venous Catheters
Humans
Antimicrobial stewardship
Pharmacology (medical)
030212 general & internal medicine
Intensive care medicine
Letter to the Editor
Aged
Coinfection
business.industry
Public health
Enterobacteriaceae Infections
COVID-19
New Delhi Metallo-beta-lactamase-producing Enterobacter cloacae
General Medicine
Middle Aged
medicine.disease
Respiration
Artificial

Anti-Bacterial Agents
Carbapenem-Resistant Enterobacteriaceae
Infectious Diseases
Female
New York City
business
geographic locations
Zdroj: International Journal of Antimicrobial Agents
ISSN: 0924-8579
DOI: 10.1016/j.ijantimicag.2020.106179
Popis: • Critically-ill COVID-19 patients with New Delhi Metallo-beta-lactamase producing Enterobacterales infections at our medical center had poor outcomes, including death in 4 of 5 cases • Multiple insults contributed to the occurrence of co-infection in these patients, including prolonged hospitalization, intubation, invasive devices, extensive antibiotic use, immunosuppressive therapy and environmental factors • There are few antibiotic options for treatment of infections with New Delhi Metallo-beta-lactamase producing Enterobacterales, contributing to poor outcomes • Hospitals and public health authorities should be vigilant for extensively drug resistant bacterial co-infections in patients hospitalized with COVID-19
Databáze: OpenAIRE