Use of high-resolution MRI of the optic nerve in Graves' ophthalmopathy
| Autor: | A W Atcha, N I Dodds, D Birchall, Alan Jackson |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
genetic structures Neuritis Graves' ophthalmopathy Optic neuropathy Optic Nerve Diseases Medicine Humans Radiology Nuclear Medicine and imaging Optic neuritis Optic canal business.industry Nerve Compression Syndromes Optic Nerve General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging eye diseases Nerve compression syndrome Graves Ophthalmopathy medicine.anatomical_structure Optic nerve sense organs business Nuclear medicine Orbit (anatomy) |
| Zdroj: | The British journal of radiology. 82(979) |
| ISSN: | 1748-880X |
| Popis: | The aim of this study was to test the hypothesis that optic neuropathy in Graves' disease is associated with measurable optic nerve compression. Magnetic resonance appearances of 32 normal subjects and 27 patients with Graves' disease were evaluated using T(1) weighted volume imaging with multiplanar reformats along the course of the optic nerve. The optic nerve diameter was measured at seven positions along its course. Patients with thyroid orbitopathy were evaluated clinically and categorised into those with (n = 6) and without (n = 48) optic neuropathy. The mean diameter of the optic nerve in normal subjects ranged from 2.2-5.2 mm. The average orbital nerve diameter decreased the further the distance from the globe within the orbit; however, it increased within the optic canal and in the pre-chiasmal region. Optic nerve diameter in patients with Graves' disease without neuritis was not significantly different from that of subjects with normal optic nerves. In patients with optic neuritis, the optic nerve was narrower throughout the length of the nerve but narrowing was most marked in the apex of the orbit (p |
| Databáze: | OpenAIRE |
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