Recurrent Deep Vein Thrombosis due to Thrombophilia
Autor: | Akm Monwarul Islam, Sam Husnayen, Afzalur Rahman |
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Rok vydání: | 2010 |
Předmět: |
Pediatrics
medicine.medical_specialty biology business.industry Deep vein Warfarin Case Report Heparin Thrombophilia medicine.disease Thrombosis Protein S Recurrent deep vein thrombosis Surgery medicine.anatomical_structure Deep vein thrombosis Internal Medicine biology.protein medicine Protein S deficiency cardiovascular diseases Cardiology and Cardiovascular Medicine business medicine.drug |
Zdroj: | Korean Circulation Journal |
ISSN: | 1738-5555 |
Popis: | Deep vein thrombosis (DVT) is a common condition that is often under-diagnosed. Acquired or hereditary defects of coagulation or a combination of these defects may facilitate the development of DVT. Recurrent DVT, a positive family history or unusual presentation may warrant investigation for hereditary thrombophilia. Investigations are best when conducted at least one month after completion of a course of anticoagulant therapy. Most patients are managed with heparin in the acute stage overlapped by warfarin. The case presented here describes a 40-year old man undergoing three episodes of DVT. Investigations revealed protein C and protein S deficiency. Protein C, protein S and antithrombin deficiency either singly or in combination, are relatively common causes of hereditary thrombophilia. The case presented here serves as a reminder of the need to look into the underlying cause of venous thromboembolism. |
Databáze: | OpenAIRE |
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