Splenopentin (DAc SP-5) — Accelerated Reconstitution of Antibody Formation after Syngeneic Bone Marrow Transplantation *)
| Autor: | Diezel W, Forner K, Eckert R, Hans-Dieter Volk, R. Schmidt |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Endocrinology
Diabetes and Metabolism Thymopoietins Mice Inbred Strains Mice Endocrinology Internal Medicine medicine Animals Bone marrow cell Bone Marrow Transplantation biology Chemistry General Medicine Syngeneic Bone Marrow Transplantation Molecular biology Peptide Fragments Thymus Hormones medicine.anatomical_structure Immunoglobulin M Splenopentin Antibody Formation biology.protein Female Bone marrow Antibody Whole-Body Irradiation Antibody formation |
| Zdroj: | Experimental and Clinical Endocrinology & Diabetes. 94:219-222 |
| ISSN: | 1439-3646 0947-7349 |
| DOI: | 10.1055/s-0029-1210901 |
| Popis: | Sublethally irradiated AB/Bln, mice (800 c Gy) and supplemented with syngeneic bone marrow cells were treated with or without a splenopentin derivative (DAc SP-5) and compared for their capacity to produce antibodies. In bone marrow cell plus DAc SP-5 treated animals antibody forming cells were found earlier and in a higher frequency than in mice treated with bone marrow cells only. These findings demonstrate that DAc SP-5 is able to induce bone marrow cell maturation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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