Bronchial responsiveness in active steelworkers
| Autor: | Thierry Bury, Renaud Louis, J. M. Kayembe, J. P. Delavignette, Jean-Louis Corhay, Adelin Albert, Georges Weber, Maurice Radermecker |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Pulmonary and Respiratory Medicine Vital capacity medicine.medical_specialty Chronic bronchitis complex mixtures Bronchial Provocation Tests Pulmonary function testing Bronchoconstrictor Agents Surveys and Questionnaires Internal medicine Prevalence Humans Medicine Bronchitis Methacholine Chloride Occupational Health Bronchus Lung business.industry Respiratory disease technology industry and agriculture medicine.disease Respiratory Function Tests respiratory tract diseases Surgery medicine.anatomical_structure Steel Bronchial hyperresponsiveness Chronic Disease Metallurgy Methacholine Bronchial Hyperreactivity business medicine.drug |
| Zdroj: | European Respiratory Journal. 11:272-277 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.98.11020272 |
| Popis: | Coke-oven workers are exposed to dust and irritant gases. Therefore they are at risk of developing lung diseases including chronic bronchitis. Nonspecific bronchial hyperresponsiveness (BHR) has been advocated as a potential risk factor predisposing to the development of chronic bronchitis. In a previous study, we showed that prevalence of BHR was higher in retired coke-oven workers than in retired blast furnace workers. The present study was carried out to determine the prevalence of BHR in active steelworkers. Thus, 137 coke-oven workers and 150 blast furnace workers underwent clinical examination, a standardized questionnaire for the study of respiratory symptoms, pulmonary function testing and methacholine aerosol challenge. The study demonstrates a higher prevalence and degree of BHR [provocative concentration of methacholine causing a 20% fall in forced expiratory volume in one second (PC20) < or = 8 mg x mL(-1)] in coke-oven workers than in blast furnace workers (31.4 versus 6.7%; p |
| Databáze: | OpenAIRE |
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