Histopathological study of cutaneous manifestations in HIV and AIDS patients
| Autor: | Sharada R Rane, Preeti Balkisanji Agrawal, Nalini Vinayak Kadgi, Meenal V Jadhav, Shaila C Puranik |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Molluscum Contagiosum HIV Infections Folliculitis Dermatology Disease Opportunistic Infections Severity of Illness Index Skin Diseases Cohort Studies Eosinophilic folliculitis Immunocompromised Host Young Adult Acquired immunodeficiency syndrome (AIDS) Eosinophilia medicine Humans Prospective Studies Young adult Developing Countries Acquired Immunodeficiency Syndrome Molluscum contagiosum Skin Diseases Vesiculobullous business.industry Pruritus Biopsy Needle Middle Aged medicine.disease Immunohistochemistry CD4 Lymphocyte Count Female Leprosy medicine.symptom business |
| Zdroj: | International Journal of Dermatology. 53:746-751 |
| ISSN: | 0011-9059 |
| Popis: | Objectives Most human immunodeficiency virus (HIV)-infected patients develop various skin diseases. These skin manifestations not only act as markers but also reflect the patient's underlying immune status. Investigating CD4 counts is costly and not always possible. Thus, the potential value to be gained by using skin manifestations as predictors of low CD4 counts and disease progression should be explored. The present study attempted to correlate the association of various cutaneous disorders found in HIV patients with CD4 and CD8 counts, the CD4 : CD8 ratio and stage of HIV infection. Methods This was a prospective study involving 61 patients who were HIV-positive and demonstrated skin lesions. Punch biopsies of skin were taken for histopathological diagnosis. CD4 and CD8 T cell counts were performed. Results The study sample included a majority of male patients, most of whom were aged 21–40 years. Pruritic papular dermatitis was the most common skin manifestation, followed by molluscum contagiosum, eosinophilic folliculitis, and Hansen's disease. Most of the lesions were associated with CD4 counts of |
| Databáze: | OpenAIRE |
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