Basal cell carcinoma treated with Mohs micrographic surgery in young Ibero-American patients
| Autor: | Abel González, María Alejandra Zuluaga, J.R. Garcés, Jorge Ocampo-Candiani, Natalia Jaimes, Maria S. Aluma-Tenorio, Veronica Ruiz-Salas, Alejandra Ávila-Álvarez, Luiz Roberto Terzian, María Carolina Tamayo-Betancur, Leonard Harry Goldberg, Natalia Caballero-Uribe, Verónica Garza-Rodríguez, Arash Kimyai-Asadi, Diana Paola Cuesta Castro |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Skin Neoplasms Adolescent medicine.medical_treatment Population Argentina Perineural invasion Skin Pigmentation Dermatology Colombia Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Mohs surgery Carcinoma Humans Medicine Neoplasm Invasiveness Basal cell carcinoma Young adult Child education Mexico Retrospective Studies education.field_of_study business.industry Incidence (epidemiology) fungi Infant Newborn Infant Retrospective cohort study Mohs Surgery medicine.disease Carcinoma Basal Cell Spain Child Preschool 030220 oncology & carcinogenesis Female Facial Neoplasms Neoplasm Recurrence Local business Brazil |
| Zdroj: | INTERNATIONAL JOURNAL OF DERMATOLOGY r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| ISSN: | 0011-9059 |
| Popis: | Background The incidence of basal cell carcinoma (BCC) in younger individuals has increased in recent decades. However, the characteristics of BCCs in this population, especially in Ibero-Latin American countries, have not been completely defined. Objective To describe the demographic, clinical, and histopathological characteristics of BCCs in patients younger than 40 treated with Mohs Micrographic Surgery (MMS). Materials and methods A multicenter, retrospective study conducted between January 2009 and December 2014, in five Ibero-American countries, included biopsy-proven BCCs in patients younger than 40 that were treated with MMS. Demographic, clinical, histopathological, and surgical characteristics were described. Results The study included 301 tumors in 241 patients, of whom 61% were female. The most common Fitzpatrick phototype was III. The most common histological subtypes were nodular (37.5%) and infiltrative (18.9%). Perineural invasion was encountered in 1.7%, and tumor clearance was achieved in 87.4% within two stages of MMS. Conclusions This is the first Ibero-Latin American transnational study describing the characteristics of BCCs in young patients treated with MMS. Despite darker skin phototypes in this population, BCCs can occur in early ages and may present with aggressive features. Therefore, MMS may be considered an appropriate first-line treatment option in this population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text