Using a model filamentous fungus to unravel mechanisms of lignocellulose deconstruction
| Autor: | Elizabeth A. Znameroski, N. Louise Glass |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Mutant
Review Computational biology Cellulase Management Monitoring Policy and Law Applied Microbiology and Biotechnology Neurospora Microbiology Neurospora crassa Hypocrea Filamentous fungus Organism Trichoderma reesei Secretome Trichoderma biology Renewable Energy Sustainability and the Environment fungi Crassa food and beverages biology.organism_classification General Energy biology.protein Transcriptome Lignocellulosic biofuels Biotechnology |
| Zdroj: | Znameroski, Elizabeth A; & Glass, N Louise. (2013). Using a model filamentous fungus to unravel mechanisms of lignocellulose deconstruction. Biotechnology for Biofuels, 6(1), 6. doi: http://dx.doi.org/10.1186/1754-6834-6-6. Retrieved from: http://www.escholarship.org/uc/item/98n7h833 Biotechnology for Biofuels |
| DOI: | 10.1186/1754-6834-6-6. |
| Popis: | Filamentous fungi are the main source of enzymes used to degrade lignocellulose to fermentable sugars for the production of biofuels. While the most commonly used organism for the production of cellulases in an industrial setting is Trichoderma reesei (Hypocrea jecorina), recent work in the model filamentous fungus Neurospora crassa has shown that the variety of molecular, genetic and biochemical techniques developed for this organism can expedite analyses of the complexities involved in the utilization of lignocellulose as a source of carbon. These include elucidating regulatory networks associated with plant cell wall deconstruction, the identification of signaling molecules necessary for induction of the expression of genes encoding lignocellulolytic enzymes and the characterization of new cellulolytic enzymatic activities. In particular, the availability of a full genome deletion strain set for N. crassa has expedited high throughput screening for mutants that display a cellulolytic phenotype. This review summarizes the key findings of several recent studies using N. crassa to further understanding the mechanisms of plant cell wall deconstruction by filamentous fungi. |
| Databáze: | OpenAIRE |
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