Patient characteristics associated with differences in radiation exposure from pediatric abdomen-pelvis CT scans: a quantile regression analysis
| Autor: | Daniel L. Lodwick, Choonsik Lee, Brent Adler, Peter C. Minneci, Jennifer N. Cooper, Katherine J. Deans |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Pediatric Obesity medicine.medical_specialty Percentile Adolescent Patient characteristics Health Informatics Effective dose (radiation) Pelvis 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Abdomen Humans Medicine Child business.industry Infant Radiation Exposure Computer Science Applications Quantile regression Radiation exposure medicine.anatomical_structure Child Preschool 030220 oncology & carcinogenesis Regression Analysis Female Radiology Tomography X-Ray Computed business Nuclear medicine Quantile |
| Zdroj: | Computers in Biology and Medicine. 85:7-12 |
| ISSN: | 0010-4825 |
| DOI: | 10.1016/j.compbiomed.2017.04.003 |
| Popis: | Computed tomography (CT) is a widely used diagnostic tool in pediatric medicine. However, due to concerns regarding radiation exposure, it is essential to identify patient characteristics associated with higher radiation burden from CT imaging, in order to more effectively target efforts towards dose reduction. Our objective was to identify the effects of various demographic and clinical patient characteristics on radiation exposure from single abdomen/pelvis CT scans in children.CT scans performed at our institution between January 2013 and August 2015 in patients under 16 years of age were processed using a software tool that estimates patient-specific organ and effective doses and merges these estimates with data from the electronic health record and billing record. Quantile regression models at the 50th, 75th, and 90th percentiles were used to estimate the effects of patients' demographic and clinical characteristics on effective dose.2390 abdomen/pelvis CT scans (median effective dose 1.52mSv) were included. Of all characteristics examined, only older age, female gender, higher BMI, and whether the scan was a multiphase exam or an exam that required repeating for movement were significant predictors of higher effective dose at each quantile examined (all p0.05). The effects of obesity and multiphase or repeat scanning on effective dose were magnified in higher dose scans.Older age, female gender, obesity, and multiphase or repeat scanning are all associated with increased effective dose from abdomen/pelvis CT. Targeted efforts to reduce dose from abdominal CT in these groups should be undertaken. |
| Databáze: | OpenAIRE |
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