Nocturnal blood pressure fluctuation and associated influential factors in severe obstructive sleep apnea patients with hypertension
| Autor: | Mao Huang, Xilong Zhang, Yanli Gu, Yongqing Hong, Jing Xu, Bing Sun, Zili Meng, Zongren Wan, Shan Zhang, Xiaochen Xie, Ning Ding, Nana Wang, Rong Zhang |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Neurology Polysomnography 030204 cardiovascular system & hematology Nocturnal Risk Assessment Arousal 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Humans Hypoxia Oxygen saturation (medicine) Sleep Apnea Obstructive business.industry Apnea Middle Aged Hypoxia (medical) medicine.disease respiratory tract diseases Obstructive sleep apnea Blood pressure Otorhinolaryngology Hypertension Cardiology Female Neurology (clinical) medicine.symptom Sleep business 030217 neurology & neurosurgery |
| Zdroj: | Sleep and Breathing. 22:1045-1052 |
| ISSN: | 1522-1709 1520-9512 |
| DOI: | 10.1007/s11325-018-1634-6 |
| Popis: | Obstructive sleep apnea syndrome (OSAS) can induce dramatic blood pressure (BP) fluctuations during sleep and it can be associated with hypertension. We investigated the properties and associated influential factors of BP fluctuation in severe OSAS with and without hypertension. Two hundred one severe OSAS subjects were divided into hypertensive and normotensive groups. BP was continuously monitored via measurement of pulse transmit time (PTT). The value of apnea-related systolic BP elevation (ΔSBP) was used to reflect the amplitude of BP fluctuation, and the SBP index (the number of ΔSBP > 10 mmHg per hour of sleep time) was used to stand for the frequency of significant BP fluctuations. Compared with the normotensive group, △SBP and SBP index were higher in the hypertensive group (13.8 ± 4.4 mmHg vs 10.9 ± 3.1 mmHg; 44.8 ± 21.3 events/h vs 26.8 ± 15.8 events/h, all p |
| Databáze: | OpenAIRE |
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