Successful improvement of Buschke-Löwenstein tumour in an HIV-infected patient with antiretroviral therapy alone
| Autor: | S. Gallien, Camille Grodner, Aurélia Henn, Jean-Daniel Lelièvre |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
Oncology medicine.medical_specialty Local excision Human immunodeficiency virus (HIV) HIV Infections Buschke-Lowenstein tumour Buschke-Lowenstein Tumor medicine.disease_cause Article Malignant transformation 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Immunity Internal medicine Hiv infected medicine Humans 030212 general & internal medicine Papillomaviridae Pelvic Neoplasms Giant condyloma acuminatum business.industry General Medicine Middle Aged medicine.disease Antiretroviral therapy Anti-Retroviral Agents business |
| Zdroj: | BMJ Case Reports. :bcr2016217753 |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2016-217753 |
| Popis: | Buschke-Löwenstein tumour (BLT), also defined as giant condyloma acuminatum, is a rare exophytic tumour affecting the anogenital and perianal regions associated with human papillomavirus (HPV) infections, with a potential of malignant transformation and which is at a greater risk in T-cell mediated immunodeficient patients. Different therapeutic options, alone or in combination, have been reported for the treatment of BLT including local therapy but wide surgical local excision is however recommended as the most important therapeutic intervention. We report a case of a HIV-infected man who developed a voluminous pelvic BLT which disappeared progressively under antiretroviral therapy with no additional treatment, contemporary to an improvement of his immunity, highlighting the possible spontaneous reversibility of HPV-induced tumours in treated HIV infection. |
| Databáze: | OpenAIRE |
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