Improving the Quality and Design of Retrospective Clinical Outcome Studies that Utilize Electronic Health Records
| Autor: | Vignesh Jayaraman Muralidharan, Jeffery S Durbin, Brendon Cornett, Oliwier Dziadkowiec, Megan Novak |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry media_common.quotation_subject Comparative effectiveness research Case-control study Retrospective cohort study Health records Outcome (game theory) Education Family medicine Medicine Quality (business) business Earth-Surface Processes Cohort study media_common |
| Zdroj: | HCA Healthc J Med |
| ISSN: | 2689-0216 |
| Popis: | Description Electronic health records (EHRs) are an excellent source for secondary data analysis. Studies based on EHR-derived data, if designed properly, can answer previously unanswerable clinical research questions. In this paper we will highlight the benefits of large retrospective studies from secondary sources such as EHRs, examine retrospective cohort and case-control study design challenges, as well as methodological and statistical adjustment that can be made to overcome some of the inherent design limitations, in order to increase the generalizability, validity and reliability of the results obtained from these studies. |
| Databáze: | OpenAIRE |
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