The Association between Air Pollution and COVID-19 Related Mortality in Santiago, Chile: A Daily Time Series Analysis
| Autor: | Sabit Cakmak, Anna Lukina, Rafael Romero-Meza, Claudia Blanco-Vidal, Robert E. Dales, Stephanie Schoen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) Epidemiology Air pollution O3 SO2 010501 environmental sciences NO2 medicine.disease_cause 01 natural sciences Biochemistry Article PM10 and PM2.5 COVID-19 03 medical and health sciences 0302 clinical medicine Interquartile range Air Pollution Environmental health medicine Humans 030212 general & internal medicine Chile Mortality Time series Risk factor Aged 0105 earth and related environmental sciences General Environmental Science Aged 80 and over Air Pollutants Ambient air pollution SARS-CoV-2 business.industry Human health COVID-19 Relative mortality Environmental Exposure Environmental exposure CO Relative risk Particulate Matter business |
| Zdroj: | Environmental Research |
| ISSN: | 1556-5068 |
| Popis: | Background: Exposure to ambient air pollution is a risk factor for morbidity and mortality from lung and heart disease. Research Question: Does short term exposure to ambient air pollution concentration influence COVID-19 related mortality? Study Design and Methodology: Using time series analyses we tested the association between daily changes in air pollution measured by stationary monitors in and around Santiago, Chile and deaths from laboratory confirmed or suspected COVID-19 between March 16 and August 31, 2020. Results were adjusted for temporal trends, temperature and humidity, and stratified by age and sex. Results: There were 10,069 COVID-19 related deaths of which 7,659 were laboratory confirmed. For an unlagged interquartile range (IQR) increase in CO, NO2 and PM2.5 the relative mortality risk (RR) estimates (95% CI) were 1.058 (1.031, 1.085), 1.063 (1.029, 1.098) and 1.061 (1.036, 1.085), respectively. There were no significant differences in RR by sex, but RR generally increased with age. In those at least 85 years old, an IQR increase in NO2 was associated with a 12.7% (95% CI 4.2, 22.2) increase in daily mortality. Interpretation: This study provides evidence that daily increases in air pollution increase the risk of dying from COVID-19, especially in the elderly. Funding Statement: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors Declaration of Interests: All authors have no competing financial interests. Ethics Approval Statement: The data were collected for administrative purposes, and were provided with no personal identifiers; hence, the present study was exempt from review by the Health Canada Research Ethics Board. |
| Databáze: | OpenAIRE |
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