Use of the Dyskinesia Impairment Scale in non‐ambulatory dyskinetic cerebral palsy

Autor: Jules G. Becher, R. Jeroen Vermeulen, Elegast Monbaliu, Karin Boeschoten, Sabine Fleuren, Helga Haberfehlner, Laura A Bonouvrié, A.I. Buizer
Přispěvatelé: MUMC+: TPZ Fysiotherapie (9), Klinische Neurowetenschappen, MUMC+: MA Med Staf Spec Neurologie (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, AMS - Rehabilitation & Development, Rehabilitation medicine, Amsterdam Movement Sciences, Amsterdam Movement Sciences - Restoration and Development, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Pediatric surgery
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
030506 rehabilitation
Baclofen
CHILDREN
Pediatrics
Severity of Illness Index
law.invention
Disability Evaluation
0302 clinical medicine
fluids and secretions
Randomized controlled trial
law
Young adult
Child
Injections
Spinal

Dystonia
INSTRUMENT
MEASURE DYSTONIA
Muscle Relaxants
Central

Intrathecal baclofen
Treatment Outcome
INTRATHECAL BACLOFEN
RELIABILITY
Original Article
Female
medicine.symptom
0305 other medical science
Life Sciences & Biomedicine
Dyskinetic cerebral palsy
CHOREOATHETOSIS
medicine.medical_specialty
Adolescent
Concurrent validity
Clinical Neurology
complex mixtures
03 medical and health sciences
Young Adult
Developmental Neuroscience
Internal medicine
Severity of illness
mental disorders
medicine
Humans
VALIDITY
Science & Technology
Dyskinesias
business.industry
Cerebral Palsy
Original Articles
medicine.disease
Dyskinesia
Pediatrics
Perinatology and Child Health

Neurology (clinical)
Neurosciences & Neurology
business
030217 neurology & neurosurgery
Zdroj: Developmental Medicine and Child Neurology
Developmental Medicine and Child Neurology, 62(4), 494-499. Wiley
Haberfehlner, H, Bonouvrié, L A, Boeschoten, K, Fleuren, S, Monbaliu, E, Becher, J G, Vermeulen, R J & Buizer, A I 2020, ' Use of the Dyskinesia Impairment Scale in non-ambulatory dyskinetic cerebral palsy ', Developmental Medicine and Child Neurology, vol. 62, no. 4, pp. 494-499 . https://doi.org/10.1111/dmcn.14415
Developmental Medicine and Child Neurology, 62(4), 494-499. Wiley-Blackwell
ISSN: 1469-8749
0012-1622
DOI: 10.1111/dmcn.14415
Popis: Aim To assess the responsiveness, concurrent validity, and feasibility of the Dyskinesia Impairment Scale (DIS) in non‐ambulatory patients with dyskinetic cerebral palsy (CP). Method The study is a secondary analysis of data collected in the IDYS trial, a randomized controlled trial on the effects of intrathecal baclofen (ITB). The DIS and Barry–Albright Dystonia Scale (BADS) were conducted at baseline and after 3 months of ITB or placebo treatment. Responsiveness was assessed by comparing the effect sizes and correlation of change after treatment between the DIS and BADS. Concurrent validity was evaluated by assessing the correlations between scales. Feasibility was evaluated for each DIS item by the number of participants who successfully accomplished the item. Results Thirty‐three non‐ambulatory patients (9 females, 24 males) with dyskinetic CP (ITB‐treated: n=17, mean [SD] age: 14y 1mo [4y 1mo]; placebo‐treated: n=16, mean [SD] age: 14y 7mo [4y]) were included in the study. The effect sizes for BADS and DIS were similar in The ITB‐treated group (−0.29 and −0.22 respectively). Changes after treatment on the DIS dystonia subscale correlated with changes on the BADS (r=0.64; p
What this paper adds The Dyskinesia Impairment Scale (DIS) and Barry–Albright Dystonia Scale showed similar responsiveness in non‐ambulatory patients with dyskinetic cerebral palsy (CP).No floor or ceiling effect was observed for DIS in non‐ambulatory participants.The concurrent validity of DIS was adequate in non‐ambulatory participants.Patients with dyskinetic CP in Gross Motor Function Classification System levels IV and V could not perform all DIS activity items.
Databáze: OpenAIRE